G3 Bioglass - A patented inorganic metal-free bioglass with proven antimicrobial effectiveness via membrane depolarization without antimicrobial resistance result
The G3® patented antimicrobial inorganic bioglass is metal and phosphorus-free and consists of a SiO2-Al2O3-Na2O-B2O3-CaO composition that has demonstrated to be very effective against Gram+, Gram-, fungi and corresponding biofilms in both relevant environments and clinical tests. It is easily and economically produced, contains no nanoparticles, and doesn't generate antimicrobial resistance due to its action principle, based on membrane depolarization instead of metal ion membrane adhesion or penetration. It does not leach metal ions or particles, and degrades as any other glass, with a useful life measured in years vs. short lived metal based solutions. It can be integrated in bulk or as additive in fibres, paints, polymers, plastics, cements and ceramics, used directly as coating on various surfaces. It is 100% biocompatible and as a coating can be used on medical devices, or as an additive in bone-grafting solutions. Upon degradation, it is even good for soils due to mineral content.
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